Four-minute forensic mysteries are solved by a cast of quirky but lovable characters. Their wisecracking leader is CSI Wes Burton who carries his evidence-gathering tools with him to each crime scene and loves his work solving problems. Crime scenes include everything from exploding flour in a restaurant kitchen, to a boy who lies about eating a piece of cake, to a man who dies accidentally while tanning himself. Burton and his coworkers use science to prove that strangulation with a towel leaves unique imprints, that antique flowers are deadly, and that insects can tell a good story.